|Interface||Command line interface|
|Restrictions to use||None|
|License||GNU General Public License version 2.0|
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- person_outline Donovan H. Parks <>
Installation can be somewhat challenging, because the tool has a fair number of dependencies that need to be installed as well. Ultimately, I chose to install it on a virtual machine running a 64 bit version of Ubuntu; I could perform most of the basic functions there, but didn't have enough RAM for some of the more computationally-intensive functions (for example, tetra, which calculates the tetranucleotide signatures).
I find the "bin_qa_plot" very useful to asses bins at a glance, and there are a variety of other useful graphical outputs to look more closely at the coverage and composition of individual bin. The tool also offers a number of ways to modify and refine bins manually, and the combination has the potential to be very powerful in recovering more complete draft genomes from metagenomes.
The tool can also be used to evaluate the results of single-cell genomics or genomes recovered from isolates, so it has broader applications than just metagenomics.