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CHEXVIS specifications


Unique identifier OMICS_08129
Interface Web user interface
Restrictions to use None
Input format PDB
Computer skills Basic
Stability No
Maintained Yes


  • person_outline Talha B. Masood

Publication for CHEXVIS

CHEXVIS citations


GABAA Receptor Coupling Junction and Pore GABRB3 Mutations are Linked to Early Onset Epileptic Encephalopathy

Sci Rep
PMCID: 5698489
PMID: 29162865
DOI: 10.1038/s41598-017-16010-3

[…] mation of the channel pore, we determined the properties of the channel cavity and the pore-lining residues along the axis of the channel pore through the implementation of the fully-automatic method ChExVis. Thus, 3D transmembrane domains of both wt and T288N receptor models in the open state were uploaded as PDB files into the ChExVis web-server using default values. The resultant transmembrane […]


Xenon for tunnelling analysis of the efflux pump component OprN

PLoS One
PMCID: 5590881
PMID: 28886086
DOI: 10.1371/journal.pone.0184045

[…] interactions are closely linked to hydrophobic notions, it appeared important to explore the hydrophobicity variation along the inner face of the tunnel. The hydropathy profile was visualized by the ChExVis program [] (), and the non-bonded energy for a xenon was calculated by rolling the atom along the tunnel axis ().Two hydrophobic regions of the tunnel are highlighted in the ChExVis diagram of […]


Analysis of aquaporins from the euryhaline barnacle Balanus improvisus reveals differential expression in response to changes in salinity

PLoS One
PMCID: 5513457
PMID: 28715506
DOI: 10.1371/journal.pone.0181192
call_split See protocol

[…] static properties and hydrophobicity/hydrophilicity were mapped. MOE was also utilized to depict residues of the constriction sites and NPA loops.Measurement of pore diameters was performed using the ChExVis software [], by uploading the generated models to the ChExVis server []. ChExVis uses a combination of Voronoi diagrams and Delauney triangulation between atoms based on their van der Waals ra […]


Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome

PMCID: 5301078
PMID: 28197552
DOI: 10.1523/ENEURO.0251-16.2017
call_split See protocol

[…] ong the pore axis (i.e., x-coordinates) and the given pore diameter profile of a channel were used to plot of pore diameters as a function of distance along the pore axis. In addition, we implemented ChExVis () ( to determine the pore radius profile and the list of the identified pore-lining residues of the transmembrane pore of the 3D structural models of th […]

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CHEXVIS institution(s)
Department of Computer Science and Automation, Indian Institute of Science, Bangalore, India

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