Gathers information about CHO protein impurities (CHOPs). CHOPPI provides a resource for assessing impurity risks related to CHOPs and their immunogenicity. The database provides an entry for each specific CHO or an entire subset of the CHO genome. Searches can be made by using the “CHOP query” mode which permits to select a specific protein or by the “genome filter” which allows filtering from a targeted CHO genome.
Department of Computer Science, Dartmouth College, Hanover, NH, USA; Institute for Immunology and Informatics, University of Rhode Island, RI, USA; EpiVax, Inc., Providence, RI, USA
CHOPPI funding source(s)
Supported by grant number U19AI082642-01 from the National Institutes of Health (NIH), the National Institute of Allergy and Infectious Diseases (NIAID) and, in part, by grant IIS- 0905206 from the National Science Foundation.