ChroMoS statistics

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Citations per year

Number of citations per year for the bioinformatics software tool ChroMoS

Tool usage distribution map

This map represents all the scientific publications referring to ChroMoS per scientific context
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ChroMoS specifications


Unique identifier OMICS_00145
Name ChroMoS
Alternative name Chromatin Modified SNPs
Interface Web user interface
Restrictions to use None
Computer skills Basic
Maintained Yes


  • person_outline Maxim Barenboim

Publication for Chromatin Modified SNPs

ChroMoS citations


A sequence based method to predict the impact of regulatory variants using random forest

BMC Syst Biol
PMCID: 5374684
PMID: 28361702
DOI: 10.1186/s12918-017-0389-1

[…] ption factor (TF) binding sites because it has been revealed that genetic variants occur in transcription factors binding sites can affect cellular phenotype and gene expression []. To mention a few, ChroMos, an integrated web-tool for SNPs classification and prioritization with the combination of genetic and epigenetic data []. HaploReg, another tool based on quantifying the difference between re […]


GWAS for serum galactose deficient IgA1 implicates critical genes of the O glycosylation pathway

PLoS Genet
PMCID: 5328405
PMID: 28187132
DOI: 10.1371/journal.pgen.1006609

[…] he top most associated variants as well as all SNPs in LD with the lead SNP (r2>0.5) at each locus. We annotated these variants using ANNOVAR[], SeattleSeq[], SNPNexus[], FunciSNP[], HaploReg4[], and ChroMos[]. The transcripts whose expressions were correlated with the lead SNPs in cis- or trans- were also identified using available eQTL datasets, including: (1) peripheral blood eQTLs based on met […]


Meta analysis of genome wide association studies discovers multiple loci for chronic lymphocytic leukemia

Nat Commun
PMCID: 4786871
PMID: 26956414
DOI: 10.1038/ncomms10933

[…] To assess chromatin state dynamics, we used Chromos, which utilizes Chip-Seq data from ENCODE on nine cell types: B-lymphoblastoid cells (GM12878), hepatocellular carcinoma cells (HepG2), embryonic stem cells (hESC), erythrocytic leukemia cells […]


Obesity related known and candidate SNP markers can significantly change affinity of TATA binding protein for human gene promoters

BMC Genomics
PMCID: 4686794
PMID: 26694100
DOI: 10.1186/1471-2164-16-S13-S5

[…] ], ACTIVITY [], is-rSNP [], RegulomeDB [], rSNP-MAPPER [], RAVEN [], SELEX_DB [], FunSeq2 [], APEG [], FeatureScan [,], SNPChIPTools [], SNP-MED [], SNAP [], FunciSNP [], SPOT [], rSNP_Guide [,], and ChroMoS [] facilitate the search for candidate SNP markers in terms of ranking of unannotated SNPs by their similarity to biomedical SNP markers in accordance with projections of these SNPs onto whole […]


A genome wide association study of marginal zone lymphoma shows association to the HLA region

Nat Commun
PMCID: 4287989
PMID: 25569183
DOI: 10.1038/ncomms6751

[…] To assess chromatin state dynamics, we used Chromos, which has precomputed data from ENCODE on nine cell types using Chip-Seq experiments. These consist of B-lymphoblastoid cells (GM12878), hepatocellular carcinoma cells (HepG2), embryonic stem […]


On the identification of potential regulatory variants within genome wide association candidate SNP sets

BMC Med Genomics
PMCID: 4066296
PMID: 24920305
DOI: 10.1186/1755-8794-7-34

[…] l. created a functional SNP annotator by incorporating ENCODE TF and histone modification datasets within an R package, FunciSNP, which was subsequently used in a breast cancer GWAS analysis [,]. The ChroMoS web server, on the other hand, facilitates SNP prioritization using genetic and epigenetic data, and predicts differential transcription factor and miRNA binding [].In this study, we introduce […]

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ChroMoS institution(s)
Bioinformatics and Deep-Sequencing Unit, Max-Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany
ChroMoS funding source(s)
National Genome Research Network (NGRN) grant (01GS1110) of the German Federal Ministry of Education and Research (BMBF)

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