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Recent studies reveal that circular RNAs (circRNAs) are a novel class of abundant, stable and ubiquitous noncoding RNA molecules in animals. Comprehensive detection of circRNAs from high-throughput transcriptome data is an initial and crucial step to study their biogenesis and function.
(Gao et al., 2015) CIRI: an efficient and unbiased algorithm for de novo circular RNA identification. Genome Biol.