Serves for the extraction of sequence-driven features from the primary protein sequence followed by the application of a classification system trained on known animal toxins. ClanTox is a systematic scheme for proteome-wide prediction of toxin-like proteins. ClanTox can be used to rank the statistically significant sequences matching toxin-like criteria. This allows the user to focus on a relatively small fraction of high-confidence candidates.
Computer Science and Engineering, Department of Biological Chemistry, Institute of Life Sciences, The Sudarsky Center for Computational Biology, The Hebrew University of Jerusalem, Israel; Blais Proteomics Center, Dana-Farber Cancer Institute, Boston, MA, USA
ClanTox funding source(s)
This work was supported by the Israel Science Foundation (ISF), the US–Israel Binational Science Foundation (BSF), and the Sudarsky Center for Computational Biology (SCCB).