Cloe HIA specifications


Unique identifier OMICS_16053
Name Cloe HIA
Software type Package/Module
Interface Graphical user interface
Restrictions to use License purchase required
Input data A simple set of early ADME and physicochemical data (aqueous solubility at one or more pH, Caco-2 apparent permeability coefficient, pKa log value(s), Log P).
Output data The predicted total absorption at several user-specified dose levels, the identification of factors (solubility and/or permeability) limiting absorption at any poorly absorbed dose level(s), the predicted dependence of the solubility on pH, the predicted absorption from the different segments of the GI tract at each dose level, the predicted time course data representing absorption over time, the predicted solubility over the pH range of the gastrointestinal tract, the peak concentration of compound achieved in the different parts of the tract.
Output format PDF, XLS
Operating system Unix/Linux
Computer skills Medium
Stability Stable
Maintained Yes


No version available


  • person_outline DDI-Fusion Team
Cloe HIA institution(s)
Cyprotex, Nether Alderley, Cheshire, UK

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