Cloe PK statistics

info info

Citations per year

Number of citations per year for the bioinformatics software tool Cloe PK
info

Tool usage distribution map

info info

Associated diseases

info

Popular tool citations

chevron_left ADMET property prediction chevron_right
Want to access the full stats & trends on this tool?

Cloe PK specifications

Information


Unique identifier OMICS_16052
Name Cloe PK
Software type Package/Module
Interface Graphical user interface
Restrictions to use License purchase required
Input data LogP (octanol/water) and pKa, microsomal intrinsic clearance, fraction unbound in plasma, blood to plasma ratio (optional), aqueous solubility, caco-2 permeability.
Output data Concentration time profiles in venous and arterial plasma, concentration time profiles in 14 organs and tissues, summary pharmacokinetic parameters.
Output format PDF, XLS
Operating system Unix/Linux
Computer skills Medium
Stability Stable
Maintained Yes

Taxon


  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus
    • Rattus norvegicus

Versioning


No version available

Maintainer


  • person_outline DDI-Fusion Team

Cloe PK citation

library_books

Physiologically based modeling of lisofylline pharmacokinetics following intravenous administration in mice

2015
PMCID: 4954844
PMID: 25663650
DOI: 10.1007/s13318-015-0260-y

[…] n from in vitro data have resulted in more frequent use of these models (Jones et al. ; Parrott et al. ). Moreover, several PBPK simulation tools have become commercially available (e.g., GastroPlus, Cloe PK, or PK-Sim).In the present study, this approach was used to evaluate plasma pharmacokinetics and tissue distribution of a drug candidate, LSF, in mice. The mean LSF concentration–time profiles […]


Want to access the full list of citations?
Cloe PK institution(s)
Cyprotex, Nether Alderley, Cheshire, UK

Cloe PK reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review Cloe PK