Clomial specifications


Unique identifier OMICS_07696
Name Clomial
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 1.16.0
Stability Stable
methods, R(>=2.10), permute, matrixStats
Maintained Yes




No version available



  • person_outline Habil Zare

Publication for Clomial

Clomial citations


Engineered in vitro cell line mixtures and robust evaluation of computational methods for clonal decomposition and longitudinal dynamics in cancer

Sci Rep
PMCID: 5647443
PMID: 29044127
DOI: 10.1038/s41598-017-13338-8

[…] PyClone 0.13.0 available from 1.3.0 available at R-bioconductor.SciClone available from available from […]


Enhancing cancer clonality analysis with integrative genomics

BMC Bioinformatics
PMCID: 4597064
PMID: 26424171
DOI: 10.1186/1471-2105-16-S13-S7

[…] es), constructs a phylogenetic tree--describing the evolution of clones within the tumor. The problem is modeled, and solutions based mathematically, on the deconvolution of a single aggregate signal.Clomial [] is another method used to infer subclonal structure using a binomial expectation maximization based approach (via somatic variant allele frequencies), and was specifically designed to deal […]

Clomial institution(s)
Department of Genome Sciences, University of Washington, Seattle, WA, USA; Division of Hematology, Department of Medicine, University of Washington, Seattle, WA, USA; Department of Biostatistics, University of Washington, Seattle, WA, USA; Department of Computer Science and Engineering, University of Washington, Seattle, WA, USA

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