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- person_outline Christopher N. Boddy
Publication for ClusterMine360
Current Status and Future Prospects of Marine Natural Products (MNPs) as Antimicrobials
[…] ntaining website links to databases and tools used in genome mining and secondary metabolism research . Automated tools such as antiSMASH  BAGEL  and PRISM  and databases such as Bactibase  ClusterMine360  and MIBiG  represent just a few of the sophisticated in silico analytical tools which have quickly established themselves as the go-to resources for BGC identification, characteriz […]
Discovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type I Polyketide Synthases Derived from Marine Microbiomes
[…] cular weight, number of amino acid monomers as well as literature references and producing organisms [,]. Another useful database of microbial polyketide and nonribosomal peptide gene clusters is the ClusterMine360 (www.clustermine360.ca). It takes advantage of crowd-sourcing by allowing researchers to make contributions into a sequence repository while automation is used to ensure high data consi […]
In silico methods for linking genes and secondary metabolites: The way forward
[…] alysis of newly identified gene clusters. Some of the major databases which have cataloged very large number of experimentally characterized PKS and NRPS clusters with known biosynthetic products are ClusterMine360, IMG-ABC and MIBiG. Apart from the sequence information and catalytic domain organization, major utility of these databases is to obtain the chemical structures of secondary metabolite […]
IMG ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites
[…] elated to biosynthetic gene clusters. GenBank records with sequences longer than 3,000 bp were retained and manually curated for their encoded SM name, whenever possible. BCs were also retrieved from ClusterMine360 () and DoBiscuit () irrespective of their length and reconciled with those retrieved from the NCBI database in order to produce a nonredundant list of BCs. The resulting BCs were mapped […]
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