CMGRN specifications

Information


Unique identifier OMICS_02199
Name CMGRN
Alternative name Constructing Multilevel Gene Regulatory Networks
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Bin Yan

Publication for Constructing Multilevel Gene Regulatory Networks

CMGRN citations

 (2)
library_books

Dynamics in Transcriptomics: Advancements in RNA seq Time Course and Downstream Analysis

2015
Comput Struct Biotechnol J
PMCID: 4564389
PMID: 26430493
DOI: 10.1016/j.csbj.2015.08.004

[…] C experiments ). Up to date, there are several multi-stage tools available to analyze RNA-seq and ChIP-seq, e.g. INsPeCT and metaseq , but only few integrated meta-dimensional approaches e.g. Beta , CMGRN and Ismara . Nevertheless, none of the mentioned methods offer specific TC algorithms for analysis, and most tools either aim to identify targets of transcription factors (TFs) and create Gene […]

library_books

Understanding gene regulatory mechanisms by integrating ChIP seq and RNA seq data: statistical solutions to biological problems

2014
PMCID: 4207007
PMID: 25364758
DOI: 10.3389/fcell.2014.00051

[…] small TF set that controls the network is obtained by solving a regularized lasso-type problem. The integration of ChIP-seq data improves the inference performance. As an alternative, as proposed in CMGRN (Guan et al., ), Bayesian network models can be first used to infer causal interrelationship among TFs and HMs (i.e., to understand how several regulators influence or associate with each other) […]

CMGRN institution(s)
Department of Biology, Hong Kong Baptist University, Hong Kong, China; Department of Internal Medicine and Biochemistry, Rush University Medical Center, Chicago, IL, USA; Department of Biochemistry and HKU-SIRI, Centre for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China; Key Laboratory of Acupuncture and Medicine Research of Minister of Education, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China
CMGRN funding source(s)
Supported by the Grant of Science Faculty of Hong Kong Baptist University [FRG2/12-13/066], National Nature Science Foundation of China [91229105], and Hong Kong Research Grants Council [781511M] and [HKBU5/CRF/11G].

CMGRN reviews

 (2)
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Anonymous user #486

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Web
Good
Anonymous user #485's avatar image No country

Anonymous user #485

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Web
a good bioinformatics tools for network