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CNS specifications

Information


Unique identifier OMICS_15605
Name CNS
Alternative name Crystallography & NMR System
Software type Package/Module
Interface Graphical user interface
Restrictions to use Academic or non-commercial use
Operating system Unix/Linux, Mac OS
Programming languages Fortran
Computer skills Medium
Version 1.3
Stability Stable
Maintained Yes

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Documentation


Maintainer


  • person_outline Axel Brunger

Publications for Crystallography & NMR System

CNS citations

 (1156)
library_books

Molecular mechanism of influenza A NS1 mediated TRIM25 recognition and inhibition

2018
Nat Commun
PMCID: 5940772
PMID: 29739942
DOI: 10.1038/s41467-018-04214-8

[…] statistics are summarised according to Trewhella et al. in Supplementary Table .PRYSPRY-CC models to fit against the experimental data were generated using a restrained MD/SA protocol implemented in CNS as previously described. In short, a template structure with CC and PRYSPRY domain connected with the 73-residue linker was generated. Then the linker (residues 361–433) was kept disordered by ran […]

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NADH/NADPH bi cofactor utilizing and thermoactive ketol acid reductoisomerase from Sulfolobus acidocaldarius

2018
Sci Rep
PMCID: 5940873
PMID: 29739976
DOI: 10.1038/s41598-018-25361-4
call_split See protocol

[…] ng a dimer from PDB 4XDZ (Ia-KARI from Ignisphaera aggregans, with 66% sequence identity to Sac-KARI) as the search model. Two clear solutions related by crystallographic symmetry were obtained using CNS. Initial rigid-body refinement based on either solution yielded an R-value of 0.45 for all data from 30 Å to 1.75 Å. The electron density map, which was calculated with a figure of merit (FOM) of […]

library_books

Structures of chaperone substrate complexes docked onto the export gate in a type III secretion system

2018
Nat Commun
PMCID: 5932034
PMID: 29720631
DOI: 10.1038/s41467-018-04137-4

[…] nts were obtained from analysis of NOE data and chemical shift information. Twenty structures with lowest target function were subjected to restrained molecular dynamics energy water refinement using CNS. The percentage of residues falling in favored and disallowed regions of the Ramachandran plot from Procheck is: 99.7% and 0.3%, respectively. The ensemble of the 15 lowest-energy conformers are s […]

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A physical catalyst for the electrolysis of nitrogen to ammonia

2018
Sci Adv
PMCID: 5922794
PMID: 29719860
DOI: 10.1126/sciadv.1700336
call_split See protocol

[…] Because nitrogen is required for the plasma-enhanced chemical vapor deposition (PECVD) synthesis of CNS (), each CNS sample always contains approximately 5% N dopants (table S1). Although N-doping is not as critical as the texture for N2 electroreduction (), it functions to raise the Fermi level of […]

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The ng_ζ1 toxin of the gonococcal epsilon/zeta toxin/antitoxin system drains precursors for cell wall synthesis

2018
Nat Commun
PMCID: 5923241
PMID: 29703974
DOI: 10.1038/s41467-018-03652-8
call_split See protocol

[…] x crystals. Phases from the Se-substructure obtained from SHELXD were improved using Phaser, Parrot and DM. An initial model was built using Coot and refined using the simulated annealing protocol of CNS. Subsequently, the model was improved in iterative cycles of manual building in Coot and refinement using Refmac. Final structure validation was performed using MolProbity. Figures were prepared u […]

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Causal Inference in the Perception of Verticality

2018
Sci Rep
PMCID: 5882842
PMID: 29615728
DOI: 10.1038/s41598-018-23838-w
call_split See protocol

[…] In the models presented above, it is assumed that the CNS either segregates (CC, SS) or fuses multisensory information (FF). CI models allow segregation and fusion to occur in tandem; the estimates generated by the different strategies are treated as int […]

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CNS institution(s)
The Howard Hughes Medical Institute and Departments of Molecular and Cellular Physiology, Neurology and Neurological Sciences, Structural Biology, and Photon Science, Stanford University, CA, USA

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