Co-LncRNA protocols

View Co-LncRNA computational protocol

Co-LncRNA statistics

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Co-LncRNA specifications

Information


Unique identifier OMICS_09948
Name Co-LncRNA
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Xia Li <>

Publication for Co-LncRNA

Co-LncRNA in pipeline

2016
PMCID: 4912721
PMID: 27317124
DOI: 10.1186/s12967-016-0926-5

[…] differentially expressed in the same hf samples, we used the dataset geo gse26887 []. we identified the mrna transcripts significantly correlated to the differentially expressed lncrnas by using co-lncrna platform [] and spearman’s rank correlation test, considering p ≤ 0.05 as statistical significance threshold. the lists of the correlated mrnas were used to predict the enriched pathways […]


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Co-LncRNA in publications

 (8)
PMCID: 5953401
PMID: 29764424
DOI: 10.1186/s12943-018-0838-5

[…] that lncrnas might modulate atgl expression. to test this hypothesis, we screened for and identified six lncrnas co-expressed with atgl in liver cancer tissues using the online software tool co-lncrna (http://www.bio-bigdata.com/co-lncrna/) []. then, we knocked down the expression of these lncrnas using sirna to examine their effect on atgl in hcc cells. the transfection efficiencies […]

PMCID: 5890391
PMID: 29657301
DOI: 10.3390/ncrna4010004

[…] in diagnosing this disease., we performed guilt by association analysis to identify potential biological pathways regulated by differentially expressed lncrna in lclc patient samples. we used a co-lncrna algorithm to identify the protein-coding genes co-expressed with lncrnas in lclc. co-regulated genes were then used to perform gene ontology (go) analysis. the go analysis identified […]

PMCID: 5678103
PMID: 29118346
DOI: 10.1038/s41598-017-14778-y

[…] (fig. ). therefore, we think linc01730 as the best candidate gene., we analyzed the potential functionality of linc01370 in silico. we performed pathway enrichment analysis using lncrna2function and co-lncrna, both of which use publicly available rna-seq data and evaluate co-expression patterns of protein-coding genes for long non-coding rnas. lncrna2function identified 391 co-expressed […]

PMCID: 5502368
DOI: 10.1093/database/bax042

[…] strategies to predict mirna functions have been published following our original publication (,). to our knowledge, only two other web tools—lncrna2function (57 samples from 2 studies) and co-lncrna (29 012 samples from 241 independent datasets)—apply this method for lncrnas. both tools follow a hypergeometric test-based approach—limited to co-expressed genes—to identify lncrna […]

PMCID: 5831932
PMID: 29657289
DOI: 10.3390/ncrna3020016

[…] databases are available to identify, study, and compare lncrnas in humans and understand the roles of these long rna species in several diseases, for example, lncipedia [], lncrnome [], co-lncrna [], starbase v2.0 [], lncrnadisease [], lnc2cancer [], etc. for comparative evaluation of these emerging tools, please refer to reviews by fritah et al., jalali et al., and yotsukura et al. […]


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Co-LncRNA institution(s)
College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China
Co-LncRNA funding source(s)
Supported by the Council of Scientific and Industrial Research (CSIR), India through Grant GENCODE-C (BSC0123).

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