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Associated diseases

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CoaSim specifications

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Unique identifier OMICS_06839
Name CoaSim
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS
Programming languages C++, Python
License GNU General Public License version 2.0
Computer skills Advanced
Stability Stable
Maintained Yes

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Publication for CoaSim

CoaSim in publications

 (3)
PMCID: 3890628
PMID: 24387001
DOI: 10.1186/1471-2105-15-3

[…] delineated by recombination hotspots along chromosomes in fine-mapping locations of disease loci. over the past decade, a plethora of coalescent simulators have been developed, e.g. selsim [], coasim [], fastcoal [], mlcoalsim [], and recoal [], to name a few. of them, five most representative and widely used coalescent simulators, hudson’s ms [], mshot [], markovian coalescent simulator […]

PMCID: 3527290
PMID: 23284294
DOI: 10.1371/journal.pgen.1003125

[…] markov model. the implementation is available as dataset s2., for our simulation experiments, we simulated ancestral recombination graphs from the coalescent with recombination process using the coasim tool . from this we extracted local (tree) genealogies and simulated sequences over these using the bio++ suite with the jukes-cantor jc69 substitution model., genome sequence alignments […]

PMCID: 1914336
PMID: 17550883
DOI: 10.1098/rspb.2007.0611

[…] selective sweep of this haplotype has occurred, we tested whether there is less variation among the resistant haplotypes than expected by chance., we used coalescent simulations (performed using coasim ()) to assess the probability that genetic diversity within the resistant haplotype conformed to the expectation under a neutral coalescent., we estimated the number of generations since […]

CoaSim institution(s)
Bioinformatics Research Center, University of Aarhus, Arhus, Denmark

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