COBEpro

[…] in the studied genomes were taken from orthomcl results., sequences of immunoreactive proteins were searched for potential epitopes using 15 predictive approaches: aap, bcpred, bepipred, cbtope, cobepro, fbcpred, igpred, svmtrip, as well as bcepred based on seven amino acid physico-chemical scales, hydrophilicity, flexibility, accessibility, turns, antigenic propensity, exposed residues […]

[…] of continuous b-cell epitopes was carried out on eight full-length vp2 amino acid sequences that were available on genbank at the time of the study (http://www.ncbi.nlm.nih.gov/genbank) with cobepro [] prediction software available from the scratch protein server (http://scratch.proteomics.ics.uci.edu/). the 8 vp2 amino acid sequences were aligned and two predicted b-cell epitope regions […]

[…] achieves auc at 0.81 and 0.85 for the fragment-based prediction and 0.57 and 0.6 for full antigen. best outperforms several modern sequence-based b-cell epitope predictors including abcpred, bcpred, cobepro, and cbtope []., svmtrip employs support vector machine to combine the tripeptide similarity and propensity scores to predict linear epitopes. svmtrip achieves a sensitivity of 80.1% […]

[…] this software allows prediction of promiscuous hla class ii binders that can bind to a large number of alleles., there are numerous methods such as bcepred [], cbtope [], lbtope [], discotope [], cobepro [] available for predicting b-cell epitopes. we employed a standalone version of lbtope software for the prediction of linear b-cell epitopes. in order to predict immune epitopes in the query […]

[…] amino acid properties, including immunoinformatic analysis and prediction of b-cell epitopes, such as hydrophilicity [], surface accessibility [], secondary structure [], flexibility [], abcpred [], cobepro [], and bepipred []. with the development of these bioinformatics methods, they provide more cost-effective approaches for seeking brucella vaccines and brucellosis diagnostic antigens., […]