COBRA Toolbox specifications


Unique identifier OMICS_06004
Name COBRA Toolbox
Alternative name COnstraints Based Reconstruction and Analysis
Software type Framework/Library, Toolkit/Suite
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages C, Fortran, MATLAB, Perl, Python, Julia
License GNU General Public License version 3.0
Computer skills Advanced
Version 3.0
Stability Stable
Maintained Yes


  • Microbiome Modeling Toolbox



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  • person_outline Ines Thiele <>

Additional information

Publications for COnstraints Based Reconstruction and Analysis

COBRA Toolbox institution(s)
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Campus Belval, Esch-sur-Alzette, Luxembourg; Division of Analytical Biosciences, Leiden Academic Centre for Drug Research, Faculty of Science, University of Leiden, Leiden, The Netherlands
COBRA Toolbox funding source(s)
Supported by the Luxembourg National Research Fund (FNR), through the ATTRACT programme (FNR/A12/01), and the OPEN grant (FNR/O16/11402054), as well as the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 757922).

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