COLT-Cancer specifications

Information


Unique identifier OMICS_03757
Name COLT-Cancer
Alternative name DPSC-Cancer
Restrictions to use None
Community driven No
Data access File download, Browse
User data submission Not allowed
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Jason Moffat

Publication for COLT-Cancer

COLT-Cancer citation

library_books

Seed effect modeling improves the consistency of genome wide loss of function screens and identifies synthetic lethal vulnerabilities in cancer cells

2017
Genome Med
PMCID: 5452371
PMID: 28569207
DOI: 10.1186/s13073-017-0440-2

[…] RIGER (RNAi gene enrichment ranking) as implemented in the GENE-E software package (http://www.broadinstitute.org/cancer/software/GENE-E/). Briefly, normalized shES scores from both Achilles 2.4 and COLT-cancer datasets were summarized to on-target genes by using the Kolmogorov–Smirnov statistic. […]

COLT-Cancer institution(s)
Banting and Best Department of Medical Research, Department of Molecular Genetics, Donnelly Centre, University of Toronto, Toronto, ON, Canada; Ontario Institute for Cancer Research, Toronto, ON, Canada
COLT-Cancer funding source(s)
Supported by Ontario Institute for Cancer Research and Terry Fox Research Institute through the Selective Therapies Program; the Canadian Institutes for Health Research #178975; the Canadian Foundation for Innovation; and the Ontario Research Fund.

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