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CoMet | A web server for comparative functional profiling of metagenomes

Offers search options for the identification of peptides and proteins in proteomics experiments. Comet implements the fast cross-correlation algorithm to score peptide sequences against experimental tandem mass spectra. The spectral pre-processing implemented in the fast-correlation algorithm eliminates the need for creating and storing theoretical spectra. Comet facilitates the analysis method of combining search results from multiple search engines.

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CoMet specifications

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Department of Genome Sciences, University of Washington, Seattle, WA, USA; Institute for Systems Biology, Seattle, WA, USA

Funding source(s)

This work was supported by NIH awards R01GM096306 (Noble) and P41GM103533 (Noble/MacCoss) and by the University of Washington's Proteomics Resource (UWPR95794).

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