Allows users to extract Protein Data Bank (PDB) information that bypasses the limitations associated with domain-based classifications. ConTemplate can suggest conformations for the query on the basis of its structural similarity to other proteins in the PDB, including proteins with low sequence similarity to the query. This tool can be applied on a genome-wide scale.
Department of Biochemistry and Molecular Biology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Israel; Department of Computer Science and Engineering, Polytechnic Institute of New York University, Brooklyn, NY, USA; The Department of Cell Research and Immunology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, Israel; Department of Computer Science, University of Haifa, Mount Carmel, Haifa, Israel
ConTemplate funding source(s)
Supported by grant No. 1775/12 of the I-CORE Program of the Planning and Budgeting Committee and the Israel Science Foundation and the Edmond J. Safra Center for Bioinformatics at Tel Aviv University.