Provides a set of hierarchical multi-layered concept of transcriptional regulation. CoryneRegNet consists of an ontology-based data warehouse. It employs a modular data processing pipeline that can recognize clusters of homologous proteins, match binding site motifs, determine operons and display special networks and graphs. This platform is useful for large-scale analysis of transcriptional regulation of gene expression in corynebacterial microorganisms.
Computational Systems Biology, Max Planck Institute for Informatics, Saarbrucken, Germany; Cluster of Excellence for Multimodal Computing and Interaction, Saarland University, Saarbrucken, Germany; Center for Biotechnology, Bielefeld University, Bielefeld, Germany; Instituto de Ciencias Biologicas, Universidade Federal de Minas Gerais, Belo Horizonte MG, Brazil
CoryneRegNet funding source(s)
Supported by DFG Cluster of Excellence for Multimodel Computing and Interaction (MMCI) and International Max Planck Research School (IMPRS).