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CpG_MPs

A comprehensive tool for identification and analysis of the methylation patterns of genomic regions from bisulfite sequencing data. CpG_MPs first normalizes bisulfite sequencing reads into methylation level of CpGs. Then it identifies unmethylated and methylated regions using the methylation status of neighboring CpGs by hotspot extension algorithm without knowledge of pre-defined regions. Furthermore, the conservatively and differentially methylated regions across paired or multiple samples (cells or tissues) are identified by combining a combinatorial algorithm with Shannon entropy.

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CpG_MPs forum

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CpG_MPs classification

CpG_MPs specifications

Software type:
Package/Module
Restrictions to use:
None
Output format:
Tab-delimited text, xls, images, genome browser
Programming languages:
Java
Stability:
Stable
Interface:
Command line interface, Graphical user interface
Input format:
Bismark output, text
Operating system:
Unix/Linux, Mac OS, Windows
Computer skills:
Advanced
Maintained:
Yes

CpG_MPs distribution

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CpG_MPs support

Maintainer

  • Yan Zhang <>

Credits

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Publications

Institution(s)

College of Bioinformatics Science and Technology, Harbin Medical University, Harbin; School of Life Science and Biotechnology, State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin, China

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