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CRISPI specifications


Unique identifier OMICS_03720
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Jacques Nicolas

Publication for CRISPI

CRISPI citations


Bacterial CRISPR Regions: General Features and their Potential for Epidemiological Molecular Typing Studies

PMCID: 5925864
PMID: 29755603
DOI: 10.2174/1874285801812010059

[…] RISPR composition, specific software applications have been developed for discovering them in prokaryotic genomes and metagenomes including CRISPR Finder, CRISPR Recognition tool (CRT), PILER-CR, and CRISPI.Among them, the CRISPR Finder is freely accessible at, a user-friendly web service that contains information about CRISPR systems in several bacterial genomes wh […]


New aspects of antiproliferative activity of 4 hydroxybenzyl isothiocyanate, a natural H2S donor

Amino Acids
PMCID: 5945766
PMID: 29508061
DOI: 10.1007/s00726-018-2546-2

[…] of molecules, i.e. specificity protein 1 (Sp1), histone deacetylase, activating protein-2 (AP-2), elongation 2 factors (E2Fs), signal transducers and activators of transcription (STATs) (Piccolo and Crispi ; Roninson ). It is known that isothiocyanates are the histone deacetylase inhibitors (Nian et al. ). It is, therefore, possible that HBITC treatment results in p21 protein expression level in […]


Genomic repeats, misassembly and reannotation: a case study with long read resequencing of Porphyromonas gingivalis reference strains

BMC Genomics
PMCID: 5771137
PMID: 29338683
DOI: 10.1186/s12864-017-4429-4

[…] ion sequence transposases were renamed as per the ISfinder [] nomenclature. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) were identified using CRISPRfinder [], CRISPRDetect [], CRISPI [] webtools and the CRT plug-in [] with Geneious. We predicted genomic islands using IslandViewer (v4) [], which has precomputed predictions from SIGI-HMM [], IslandPath [], and IslandPick []. […]


Evaluation of Abdominal Fetal Electrocardiography in Early Intrauterine Growth Restriction

Front Physiol
PMCID: 5483441
PMID: 28694782
DOI: 10.3389/fphys.2017.00437

[…] s suggest that cardiovascular changes may be present during the prenatal period with evidence of cardiac remodeling in the form of increased transverse diameters and more globular cardiac ventricles (Crispi et al., ). These corroborate with earlier descriptions of fetal hemodynamic adaptive changes in IUGR (Verburg et al., ) wherein the standard assessment of cardiac function utilizes various bioc […]


An Overview of Two Component Signal Transduction Systems Implicated in Extra Intestinal Pathogenic E. coli Infections

PMCID: 5422438
PMID: 28536675
DOI: 10.3389/fcimb.2017.00162

[…] tly disease in cows is clinical mastitis (Rollin et al., ). Clinical mastitis in an inflammation of the udders due to blockage or infection that results in visually abnormal milk production (Thompson-Crispi et al., ). The mammary pathogenic E. coli or MPEC are predominant bacteria in clinical mastitis (Shpigel et al., ).Horses have been reported to have both hemorrhagic pneumonia and soft tissue E […]


Sodium Octanoate Modulates the Innate Immune Response of Bovine Mammary Epithelial Cells through the TLR2/P38/JNK/ERK1/2 Pathway: Implications during Staphylococcus aureus Internalization

PMCID: 5350129
PMID: 28361042
DOI: 10.3389/fcimb.2017.00078

[…] Cs) are responsible for the production of milk and their response is critical for prompt bacterial clearance and prevention of mastitis (inflammation of the mammary gland) (Brenaut et al., ; Thompson-Crispi et al., ). S. aureus is a major pathogen in many animal species and represents one of the leading causes of clinical and subclinical bovine mastitis, which usually is chronic (Kerro Dego et al. […]


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CRISPI institution(s)
IRISA-INRIA, Campus de Beaulieu, Rennes, France; UMR 6197 Microbiologie des environnements extrêmes, technopôle Brest-Iroise, Plouzané, France
CRISPI funding source(s)
ANR (Agence Nationale de la Recherche) through its MODULOME project

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