CRISPResso2 specifications


Unique identifier OMICS_31666
Name CRISPResso2
Interface Web user interface
Restrictions to use Academic or non-commercial use
Input data Some raw sequencing files.
Input format FASTQ
Output data Some reports describing frequencies and efficiencies of base editing activity, plots showing base substitutions across the entire amplicon region and nucleotide substitution frequencies for a region specified by the user.
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Luca Pinello <>

Publication for CRISPResso2

CRISPResso2 institution(s)
Broad Institute of MIT and Harvard, Cambridge, MA, USA; Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA; Department of Pathology, Harvard Medical School, Boston, MA, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA; Division of Hematology/Oncology, Boston Children’s Hospital, Boston, MA, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA; Harvard Stem Cell Institute, Cambridge, MA, USA
CRISPResso2 funding source(s)
Supported by DARPA HR0011-17-2-0049; U.S. NIH RM1 HG009490, R01 EB022376, and R35 GM118062; HHMI, NIDDK (R03DK109232), NHLBI (DP2OD022716, P01HL32262), Burroughs Wellcome Fund, Doris Duke Charitable Foundation, the National Science Foundation National Institutes of Health R00HG008399 and the Defense Advanced Research Projects Agency HR0011-17-2-0042.

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