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The structural, functional, and mechanistic characterization of several types of post-translational modifications (PTMs) is well-documented. PTMs, however, may interact or interfere with one another when regulating protein function. Yet, characterization of the structural and functional signatures of their crosstalk has been hindered by the scarcity of data.
(Pejaver et al., 2014) The structural and functional signatures of proteins that undergo multiple events of post-translational modification. Protein Sci.