CRYP-SKIP statistics

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Citations per year

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Associated diseases

Associated diseases

CRYP-SKIP specifications


Unique identifier OMICS_09621
Interface Web user interface
Restrictions to use None
Input data Single/multiple sequences
Input format FASTA
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Igor Vořechovský <>

Publications for CRYP-SKIP

CRYP-SKIP in publications

PMCID: 5816747
PMID: 29487616
DOI: 10.3389/fgene.2018.00043

[…] > g) is located at the exon–intron boundary, a potential splicing donor site. therefore, in silico splicing analysis of this variation was performed by using two different web-based programs, cryp-skip and berkeley drosophila genome project (bdgp). mutations in splicing sites generally lead to exon skipping or activation of cryptic splice sites. the cryp-skip analysis showed […]

PMCID: 5716214
PMID: 28981879
DOI: 10.1093/nar/gkx824

[…] ( (). the 5′ splice sites were also scored using the hbond score web interface, version 3.4 ( cryp-skip prediction algorithm was used to determine whether a splicing mutation of interest would result in exon skipping or activation of cryptic/di novo splice sites ()., to examine the effect […]

PMCID: 4748509
PMID: 26904698
DOI: 10.1177/2324709615598167

[…] ( to predict putative 5′ splice donor and 3′ splice acceptor sites. potential exon-skipping and activation of cryptic splice sites were predicted using cryp-skip ( both wild-type and mutant flanking intronic sequences of exon 10 of the phex gene were subjected to analysis using default parameters., direct sequencing […]

PMCID: 3984245
PMID: 24728384
DOI: 10.1371/journal.pone.0094848

[…] aberrations was done using two different web-based programs designed to detect putative splice sites, taking into account branch points, exonic and intronic motifs, and several regulatory proteins. cryp-skip ( was used to estimate the probability of cryptic splice-site activation (pcr-e) and exon skipping (1-pcr-e) as a result of splicing mutations . the cryp-skip […]

PMCID: 4029872
PMID: 24263461
DOI: 10.1038/gim.2013.176

[…], free registration required): information theory-based models by which changes in the affinity of potential splice and regulatory sites caused by mutation are calculated; cryp-skip ( multiple logistic regression model which distinguishes exons that are skipped and that activate cryptic splice sites as a result of splicing mutations; […]

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CRYP-SKIP institution(s)
University of Southampton School of Medicine, Division of Human Genetics Mailpoint, Southampton, UK

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