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CS-AMPPred

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Achieves antimicrobial peptide predictions with enhanced reliability based on support vector machine (SVM) Light, showing an accuracy of 90% (polynomial model). CS-AMPPred is based on five sequence descriptors: indexes of (i) a-helix and (ii) loop formation; and averages of (iii) net charge, (iv) hydrophobicity and (v) flexibility. It can be helpful for revealing the antimicrobial activity from multifunctional peptides and for a prediction prior to synthesis of some predicted proteins in protein databases.

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CS-AMPPred classification

CS-AMPPred specifications

Software type:
Toolkit/Suite
Restrictions to use:
None
Operating system:
Unix/Linux
License:
GNU General Public License version 3.0
Stability:
Stable
Interface:
Graphical user interface
Input data:
FASTA
Programming languages:
Perl
Computer skills:
Medium
Maintained:
Yes

CS-AMPPred distribution

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CS-AMPPred support

Maintainer

  • Octavio Franco <>

Credits

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Publications

Institution(s)

Centro de Analises Proteomicas e Bioquımicas, Pos-Graduacao em Ciencias Genomicas e Biotecnologia Universidade Catolica de Brasılia, Brasılia-DF, Brazil

Funding source(s)

This work was supported by CNPq (Conselho Nacional de Desenvolvimento Cientıfico e Tecnologico); CAPES (Coordenacao de Aperfeicoamento de Pessoal de Nıvel Superior); FAPDF (fundacao de Amparo a Pesquisa do Distrito Federal) and UCB (Universidade Catolica de Brasılia).

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