An interactive plugin for Cytoscape that can be used to search, explore, analyse and visualise human Disease Comorbidity Network (DCN). CytoCom represents disease-disease associations in terms of bipartite graphs and provides ICD9 (International Classification of Diseases, Ninth Revision)-centric and disease name centric views of disease information. It allows users to find associations between diseases based on the two measures: Relative Risk (RR) and varphi-correlation values. In the disease network, the size of each node is based on the prevalence of that disease. CytoCom is capable of clustering disease network based on the ICD9 disease category. It provides user-friendly access that facilitates exploration of human diseases, and finds additional associated diseases by double-clicking a node in the existing network. Additional comorbid diseases are then connected to the existing network. It is able to assist users for interpretation and exploration of the human diseases by a variety of built-in functions. Moreover, CytoCom permits multi-coloring of disease nodes according to standard disease classification for expedient visualisation.