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In past number of methods have been developed to predict antigenic regions for designing subunit vaccines. Stimulation of T-helper cells is crucial for designing immunotherapy or vaccine. Number of in silico methods have been developed for predicting MHC Class II binders, in last decade, in order to identify T-helper epitope that may simulate T-helper cells. IL4pred is designed for users working in the field of subunit vaccine. This web server has been developed that allows users to design, discover and mapping of peptides that may induce IL4.