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In the past, numerous methods have been developed to predict MHC class II binders or T-helper epitopes for designing the epitope-based vaccines against pathogens. In contrast, limited attempts have been made to develop methods for predicting T-helper epitopes/peptides that can induce a specific type of cytokine.
(Nagpal et al., 2017) Computer-aided designing of immunosuppressive peptides based on IL-10 inducing potential. Sci Rep.