Cytosplore statistics

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Citations per year

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Tool usage distribution map

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Associated diseases

Associated diseases

Cytosplore specifications


Unique identifier OMICS_22333
Name Cytosplore
Software type Application/Script
Interface Graphical user interface
Restrictions to use Academic or non-commercial use
Operating system Windows
Programming languages C++
Computer skills Medium
Version 1.0.2
Stability Stable
Maintained Yes


  • HSNE (Hierarchical Stochastic Neighbor Embedd


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Additional information

Publications for Cytosplore

Cytosplore in publications

PMCID: 5768196
PMID: 29367854
DOI: 10.3389/fimmu.2017.01953

[…] and klrg1 were purchased from bd biosciences, biolegend, or ebioscience. cells were acquired using a bd lsr fortessa flow cytometer, and data were analyzed using flowjo software (treestar) and cytosplore (). dead cells were excluded using live/dead markers. gating strategies were performed as described (, )., the following class i-restricted peptides were used: m45985–993, m139419–426, […]

PMCID: 5700955
PMID: 29170529
DOI: 10.1038/s41467-017-01689-9

[…] representation of the complete data that preserves the non-linear high-dimensional relationships between cells. we implemented hsne in an integrated single-cell analysis framework called cytosplore+hsne. this framework allows interactive exploration of the hierarchy by a set of embeddings, two-dimensional scatter plots where cells are positioned based on the similarity of all marker […]

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Cytosplore institution(s)
Department of Immunohematology and Blood T ransfusion, Leiden University Medical Center, Albinusdreef, Leiden, Netherlands; Computer Graphics and Visualization Group, Delft University of Technology, Delft, Netherlands; Computational Biology Center, Leiden University Medical Center, Albinusdreef, Leiden, Netherlands; Pattern Recognition and Bioinformatics Group, Delft University of Technology, Delft, Netherlands; Division of Image Processing, Department of Radiology, Leiden University Medical Center, Albinusdreef, Leiden, Netherlands
Cytosplore funding source(s)
Supported by the Leiden University Medical Center, the Netherlands Organization for Scientific Research (ZonMW grant 91112008) and the Technology Foundation STW, the Netherlands (VAnPIRe; grant 12720, and Genes in Space; grant 12721).

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