Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 20
Release date: Sep 19 2017
Last update date: Nov 20 2018
Access: Public
Diseases: Alzheimer Disease, Amyotrophic Lateral Sclerosis, Tooth Loss, Neurodegenerative Diseases, X-Linked Combined Immunodeficiency Diseases
Dataset link The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases IV

Experimental Protocol


Illumina NextSeq500 was used to identify disease-associated vs. homeostatic molecular microglia signature in microglia in different disease models and transgenic models. Bulk microglia (1,000 cells/sample) FCRLS+ sorted microglia.

Repositories


GEO

GSE102562

ENA

SRP115307

BioProject

PRJNA398040

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Contact


Oleg Butovsky