Computational protocol: Establishing a yeast-based screening system for discovery of human GLUT5 inhibitors and activators

Similar protocols

Protocol publication

[…] GLUT5 model structures of inward- and outward-facing conformations were generated with COOT on the basis of crystal structure of bovine GLUT5 (PDB ID 4YB9) for the inward-facing conformation and mouse GLUT5 (PDB ID 4YBQ) for the outward-facing conformation. Energy minimization of mutant structures was performed with Phenix. […]

Pipeline specifications

Software tools Coot, PHENIX
Application Protein structure analysis