Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 24
Release date: May 18 2011
Last update date: Oct 29 2018
Access: Public
Diseases: Breast Neoplasms, Neoplasms
Chemicals: Estradiol
Dataset link Gene expression profiles of MCF-7 cells treated with Si-Wu-Tang, estradiol and ferulic acid

Experimental Protocol


We profiled the gene expression of MCF-7 cell lines to SWT, its active component FA, as well as estradiol using Affymetrix human genome U133 plus 2.0 arrays. The data set includes profiles for 24 samples, divided into eight groups of treatment: 0.001% DMSO used as the vehicle control (C), 0.1 µM estradiol (EM), FA at three concentrations (0.1, 1, and 10 µM) (FL, FM and FH) and SWT at three concentrations (0.0256, 0.256, and 2.56 mg/ml) (SL, SM and SH). For each treatment group, 3 biological replicates were included, resulting in 24 (8 groups × 3 replicates/group) RNA samples.

Repositories


GEO

GSE23610

ArrayExpress

E-GEOD-23610

BioProject

PRJNA129951

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Contact


Leming Shi

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