Computational protocol: The LetA/S two-component system regulates transcriptomic changes that are essential for the culturability of Legionella pneumophila in water

Similar protocols

Protocol publication

[…] NCBI Conserved Domain Database (CDD was used to search for conserved protein domains that may be implicated in signal sensing within LetS. The Accession number YP_095929.1 representing Lpg1912 of Legionella pneumophila Philadelphia-1 strain was queried. The TMHMM server v. 2.0 ( and TOPCONS ( were used to predict the transmembrane helices on the N-terminal of LetS,. […]

Pipeline specifications

Software tools TMHMM, TOPCONS
Databases CDD
Application Membrane protein analysis
Organisms Legionella pneumophila