|Application:||Gene expression microarray analysis|
|Number of samples:||9|
|Release date:||Sep 8 2014|
|Last update date:||Aug 23 2018|
|Diseases:||Leukemia, Leukemia, Biphenotypic, Acute, Leukemia, Myeloid, Acute, Coinfection|
|Dataset link||Assesment of gene expression upon AF10 deletion in MLL-AF9 secondary leukemia|
Primary MLL-AF9 leukemias in the AF10 floxed background (homozygous) were transduced with MSCV-IRES-tdTomato (MIT) or the Cre recombinase expressing MIT vector, cells were sorted and injected into secondary recipient mice to generate Af10 floxed (MIT) or deleted (CRE) leukemias. BM cells fresly harvested from these leukemias were sorted for tdTomato expression and used for microarrays. BM cells from Hoxa9-Meis1 transduced primary leukemias were used for comparison.