Computational protocol: Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling

Similar protocols

Protocol publication

[…] The structure of the synthetic peptide KB-752 bound to Gαi1 (PDB:1Y3A) was used as the template to generate the modeling project in Deep View/Swiss-PdbViewer v3.7 for Daple (aa 1668–1679) in complex with Gαi3. The modeling project was submitted to the Swiss-Model Server (http://swissmodel.expasy.org//SWISS-MODEL.html) (), and model images were generated by MolsoftICM (San Diego, CA). […]

Pipeline specifications

Software tools Swiss-PdbViewer, SWISS-MODEL
Databases ExPASy
Application Protein structure analysis
Diseases Neoplasms, Colorectal Neoplasms