|Application:||Gene expression microarray analysis|
|Number of samples:||10|
|Release date:||Sep 17 2012|
|Last update date:||Aug 9 2018|
|Diseases:||Hodgkin Disease, Lymphoma, Neoplasms, Lymphoma, B-Cell, Epstein-Barr Virus Infections|
|Dataset link||Analyzing primary Hodgkin and Reed-Sternberg cells to capture the molecular and cellular pathogenesis of classical Hodgkin lymphoma|
The present study complements the GSE12453 and GSE14879 records by adding the following 10 samples: 5 primary tumor samples and 5 cell line samples. The 5 primary tumor samples represent 1000-2000 neoplastic cells microdissected from frozen biopsies of 5 cases of primary mediastinal B-cell lymphoma (PMBL). The 5 cell line samples represent 500-1000 living neoplastic cells isolated by fluorescence-activated cell sorting from growing cultures of the classical Hodgkin lymphoma (cHL) cell lines L1236, L428, KMH2 and HDLM2 and the lymphocyte-predominant Hodgkin lymphoma (lpHL) cell line DEV.