Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 19
Release date: Dec 5 2011
Last update date: Aug 23 2018
Access: Public
Diseases: Brain Neoplasms, Hyperaldosteronism, Medulloblastoma, Neoplasms
Dataset link An Animal Model of Myc-driven medulloblastoma

Experimental Protocol


19 mouse cell samples (stem cells and tumor cells) were analyzed. There are four groups of samples, three with five biological replicates and the last with four (one outlier was removed). To gain insight into the mechanisms of transformation into tumors, we compared the gene expression profiles of MP tumor cells derived from stem cells (Myc/DNp53-infected Prom1+Lin- cells, designated MP-pl) or progenitors (Myc/DNp53-infected Prom1+ cells, designated MP-p) to gene expression profiles of uninfected stem cells (designated NSC) and profiles from a distinct model of medulloblastoma, the patched mutant mouse (designated ptch1).

Repositories


GEO

GSE34126

ArrayExpress

E-GEOD-34126

BioProject

PRJNA149881

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Contact


Alexey Eroshkin
Alexey M Eroshkin