|Application:||Gene expression microarray analysis|
|Number of samples:||19|
|Release date:||Dec 5 2011|
|Last update date:||Aug 23 2018|
|Diseases:||Brain Neoplasms, Hyperaldosteronism, Medulloblastoma, Neoplasms|
|Dataset link||An Animal Model of Myc-driven medulloblastoma|
19 mouse cell samples (stem cells and tumor cells) were analyzed. There are four groups of samples, three with five biological replicates and the last with four (one outlier was removed). To gain insight into the mechanisms of transformation into tumors, we compared the gene expression profiles of MP tumor cells derived from stem cells (Myc/DNp53-infected Prom1+Lin- cells, designated MP-pl) or progenitors (Myc/DNp53-infected Prom1+ cells, designated MP-p) to gene expression profiles of uninfected stem cells (designated NSC) and profiles from a distinct model of medulloblastoma, the patched mutant mouse (designated ptch1).
Alexey M Eroshkin