Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 16
Release date: Dec 11 2015
Last update date: Aug 23 2018
Access: Public
Diseases: Congenital Abnormalities, Cleft Palate, Tongue Diseases
Genes: TLF, MAPK1
Dataset link Gene expression profiling of the palate in Erk2 mutant mouse models

Experimental Protocol


To investigate the adverse effects of dysfunctional ERK signaling on the cellular metabolism of palatal mesenchyme during palatogenesis, we analyzed mice with a neural crest cell-specific conditional inactivation of Erk2 (Erk2fl/fl;Wnt1-Cre). We performed microarray analyses of primary mouse embryonic palatal mesenchymal cells of Erk2fl/fl;Wnt1-Cre mutant mice and Erk2fl/fl control mice, collected at embryonic day 13.5 (n=3 per genotype) and E14.5 (n=5 per genotype).

Repositories


GEO

GSE67087

ArrayExpress

E-GEOD-67087

BioProject

PRJNA278879

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Contact


Maria Ruiz-Echevarria