Computational protocol: Relationship between microRNA-146a expression and plasma renalase levels in hemodialyzed patients

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Protocol publication

[…] All statistical analyzes were conducted using Statistica 10.0 software (StatSoft, Poland) and MedCalc version 12.7 (MedCalc software, Belgium). All values were expressed as the mean and standard deviation (SD). The distribution of the analyzed variables was tested using the Shapiro—Wilk test. Fisher’s exact test was used to compare groups of patients with different miRNA expression and biochemical factors concentration. The Kaplan—Meier estimator with log-rank test analysis was used to correlate patients’ overall survival with different molecular and biochemical factors. Pearson’s correlation coefficient was applied to correlate miRNAs expression level with renalase concentration. Furthermore, the statistical relationship between the two variables was investigated using Spearman’s correlation coefficient R. In all tests, P-value < 0.05 was considered statistically significant for differences or correlations confirmation. […]

Pipeline specifications

Software tools Statistica, MedCalc
Application Miscellaneous
Organisms Homo sapiens
Diseases Heart Diseases
Chemicals Amino Acids