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Searches the linear information in proteins. DALEL utilizes a novel parallel and recursive algorithm that allows divide the exploding space of enumeration and degeneration into much smaller spaces that can be built and searched very fast and in parallel. First, it enumerates all possible motifs of variable length including any number and combination of wildcards. Then, it degenerates the motifs to discover conserved and flexible individual and correlated residues.

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If you have a set of related proteins sharing a common behavior (e.g., sharing a common binding partner), and you are interested in identifying the short linear peptides (e.g. binding sites) in their sequences that might be involved in that behavior, so DALEL is the perfect tool for you.

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DALEL classification

DALEL specifications

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DALEL support


  • Stephen Michnick <>


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Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada; Department of Biochemistry and Molecular Medicine, University of Montreal, Montreal, Quebec, Canada; Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel

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