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Protocols

DAPD specifications

Information


Unique identifier OMICS_31282
Name DAPD
Alternative name Diabetes Associated Proteins Database
Restrictions to use None
Database management system MySQL
Community driven No
Data access File download, Browse
User data submission Not allowed
Maintained Yes
Availability Yes

Maintainers


  • person_outline Krishnasamy Gopinath
  • person_outline Muthusamy Karthikeyan

Publication for Diabetes Associated Proteins Database

DAPD citations

 (3)
library_books

L,L diaminopimelate aminotransferase (DapL): a putative target for the development of narrow spectrum antibacterial compounds

2014
Front Microbiol
PMCID: 4176475
PMID: 25309529
DOI: 10.3389/fmicb.2014.00509

[…] However, suitable orthologs for the other genes known to be involved in the DAP/lys (dapA, dapB, dapF, and lysA) pathway were readily identified (Hudson et al., ). In addition, enzymatic activity of DapD and DapC could not be detected from crude protein extracts prepared from Glycine max, Zea mays, Nictotiana tobacum, and Chlamydomonas reinhardtii, yet the extract from Z. mays was able to synthes […]

library_books

High Throughput Screening of a Corynebacterium glutamicum Mutant Library on Genomic and Metabolic Level

2014
PLoS One
PMCID: 3913579
PMID: 24504095
DOI: 10.1371/journal.pone.0086799

[…] he glnE mutant indicate a connection of the 2,6-diaminopimelate synthesis to the regulation of the GS/GOGAT system. As the 2,6-diaminopimelate production involving tetrahydrodipicolinate succinylase (DapD, EC 2.3.1.117) is regulated dependent on the nitrogen supply (), it seems that the inactivation of the glutamate-ammonia ligase adenylyltransferase or the resulting increased activity of the glut […]

call_split

Tetrahydrodipicolinate N Succinyltransferase and Dihydrodipicolinate Synthase from Pseudomonas aeruginosa: Structure Analysis and Gene Deletion

2012
PLoS One
PMCID: 3281039
PMID: 22359568
DOI: 10.1371/journal.pone.0031133
call_split See protocol

[…] other water molecules. Well defined difference electron density allowed modeling of CoA and succinate for the CoA-succinate complex of PaDapD. The final model of this complex contains three chains of DapD, amino acid residues 1–245 and 251–343, three CoA and succinate molecules and 147 water molecules. No electron density was observed for the loop comprising residues 246–250. The electron densitie […]

Citations

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DAPD institution(s)
Department of Bioinformatics, Science Block, Alagappa University, Karaikudi, India; Department of Botany, Government Arts College, Melur, India
DAPD funding source(s)
Supported by Post Graduate Diploma in Structural Pharmacogenomics (funded by UGC Innovative Program, UGC, Government of India) and Department of Bioinformatics, Alagappa University, Karaikudi, India.

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