DARIO statistics

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Citations per year

Number of citations per year for the bioinformatics software tool DARIO

Tool usage distribution map

This map represents all the scientific publications referring to DARIO per scientific context
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Associated diseases


Popular tool citations

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DARIO specifications


Unique identifier OMICS_00356
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Steve Hoffmann

Publication for DARIO

DARIO citations


The discovery potential of RNA processing profiles

Nucleic Acids Res
PMCID: 5814818
PMID: 29155959
DOI: 10.1093/nar/gkx1115

[…] h included the execution of Blockbuster (), took ∼15 min and used nearly 30 Gb of memory. Additionally, we compared the performance of SeRPeNT against the supervised version of BlockClust and against DARIO (), using a cross-fold validation approach (). Using small RNA-Seq data from MCF-7 cells () (GSM769510) for the three methods, SeRPeNT shows overall higher precision in all tested sncRNA familie […]


Circulating microRNAs and Bioinformatics Tools to Discover Novel Diagnostic Biomarkers of Pediatric Diseases

PMCID: 5615367
PMID: 28925938
DOI: 10.3390/genes8090234

[…] of small RNA expression by means of NGS approaches, downstream data analysis might be performed using different tools: small RNA toolkit [], miRDeep [] and miRDeep2 [], miRanalyzer [,], SeqBuster [], DARIO [] UEA sRNA workbench [] and ShortStack []. In certain cases, some of these tools include other prediction tools for novel microRNAs or isoforms of miRNAs (isomiRs) quantification. However, they […]


miRDis: a Web tool for endogenous and exogenous microRNA discovery based on deep sequencing data analysis

Brief Bioinform
PMCID: 5952930
PMID: 28073746
DOI: 10.1093/bib/bbw140

[…] ate (FDR), long running time or nonintuitive to use. For example, because of the common concern that multi-genome comparison normally requires significant long computing time, Web-based tools such as DARIO [], sRNAbench [] and Chimira [] limit the user submission by one sample per job and/or file upload size <500 MB or 1.6 GB, while the well-designed stand-alone packages, e.g. CAP-miRSeq [], requi […]


Computational Approaches for the Analysis of ncRNA through Deep Sequencing Techniques

Front Bioeng Biotechnol
PMCID: 4453482
PMID: 26090362
DOI: 10.3389/fbioe.2015.00077

[…] ent length, cleavage specificity, and antisense transcription, CoRAL can effectively classify six distinct ncRNA classes among miRNAs and transposon-derived RNAs. Outperforming previous tools such as DARIO and miRDeep2, CoRAL provides the opportunity to annotate ncRNAs in other less well-characterized organisms.Another tool for ncRNA annotation in NGS data lacking reference genomes is the software […]


Revealing stable processing products from ribosome associated small RNAs by deep sequencing data analysis

Nucleic Acids Res
PMCID: 3351166
PMID: 22266655
DOI: 10.1093/nar/gks020

[…] e clustering of the contigs not only clarifies the result list but also solves the problem of normalization of the read count. In existing pipelines for annotation of ncRNA deep-sequencing data, like DARIO (), the multiple matching reads are normalized by number of mappings. By employing the read name-based contig clustering the spurious read mappings are removed, thus such artificial normalizatio […]

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DARIO institution(s)
Interdisciplinary Center for Bioinformatics and Bioinformatics Group, Department of Computer Science, University Leipzig, Leipzig, Germany; LIFE, Leipzig Research Center for Civilization Diseases, University Leipzig, Leipzig, Germany
DARIO funding source(s)
LIFE - Leipzig Research Center for Civilization Diseases, Universität Leipzig. European Social Fund and the Free State of Saxony

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