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Read simulation software tools | Bisulfite sequencing data analysis

As the number of studies looking at differences between DNA methylation increases, there is a growing demand to develop and benchmark statistical methods to analyse these data. To date no objective approach for the comparison of these methods has…
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DNemulator
Desktop

DNemulator

A package for simulating DNA sequencing errors, polymorphisms, cytosine…

A package for simulating DNA sequencing errors, polymorphisms, cytosine methylation and bisulfite conversion. DNemulator simulates polymorphisms based on real polymorphisms and their frequencies,…

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WGBSSuite
Desktop

WGBSSuite

A flexible stochastic simulation tool that generates single-base resolution DNA…

A flexible stochastic simulation tool that generates single-base resolution DNA methylation data genome-wide. Several simulator parameters can be derived directly from real datasets provided by the…

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methInheritSim
Desktop

methInheritSim

Simulates whole-genome inherited bisulphite sequencing data. MethInheritSim…

Simulates whole-genome inherited bisulphite sequencing data. MethInheritSim simulates a multi-generation methylation case versus control experiment with inheritance relation using a real control…

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Sherman
Desktop

Sherman

A tool to simulate FastQ files for high-throughput sequencing experiments.

A tool to simulate FastQ files for high-throughput sequencing experiments.

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FastqToBS
Desktop

FastqToBS

A simple and useful program (command line) to virtually treat with bisulfite a…

A simple and useful program (command line) to virtually treat with bisulfite a fastq file. Can be combined with existing NGS simulators to simulate BS-treated reads.

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BSSim
Desktop

BSSim

Simulates genetic variations that are divergent from reference sequence along…

Simulates genetic variations that are divergent from reference sequence along with the sequencing error and quality distributions. BSSim is a BS-seq simulator that provides output read datasets for…

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