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Contains the most comprehensive information to date on human small non-coding RNAs (sncRNA) genes and mature sncRNA products. DASHR provides a simple user interface for researchers to view sequence and secondary structure, compare expression levels, and evidence of specific processing across all sncRNA genes and mature sncRNA products in various human tissues. DASHR annotation and expression data covers all major classes of sncRNAs including microRNAs (miRNAs), Piwi-interacting (piRNAs), small nuclear, nucleolar, cytoplasmic (sn-, sno-, scRNAs, respectively), transfer (tRNAs), and ribosomal RNAs (rRNAs). DASHR is distinct from other existing databases because it integrates annotations for all major classes of sncRNAs with baseline expression profiles in different human tissues and cell types, making it a very useful resource to the broader scientific community.

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Maintainer

  • Li-San Wang <lswang at mail.med.upenn.edu>

Institution(s)

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Penn Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA 19104, USA; Genomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Computer and Information Science, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute on Aging, University of Pennsylvania, Philadelphia, PA 19104, USA

Funding source(s)

National Institute of General Medical Sciences [R01-GM099962]; National Institute on Aging [U24-AG041689 and U01-AG032984]; Penn Alzheimer’s Disease Center [P30-AG10124]; National Science Foundation [MCB-1053846]

  • (Leung et al., 2015) DASHR: database of small human noncoding RNAs. Nucleic acids research.
    PMID: 26553799
  • Animals
    • Homo sapiens

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