|Application:||Gene expression microarray analysis|
|Number of samples:||6|
|Release date:||Jan 15 2009|
|Last update date:||Oct 29 2018|
|Diseases:||Neoplasms, Prostatic Neoplasms|
|Dataset link||Expression profile of PC-3-derived cell lines after transendothelial migration|
We wanted to compare the expression profiles of cells that had undergone transendothelial migration. The parental, and reference cell line, PC-3 was plated onto a confluent human microvascular endothelial cell line from the lung and allowed to migrate across this monolayer. A new cell line, TEM4-18, was isolated from this experiment. We also performed this experiment a second time to isolate a biological replicate of the TEM4-18 cell line, termed TEM2-5. All 3 cell lines, PC-3, TEM4-18, and TEM2-5 are analyzed as replicates in this experiment for a total of 6 samples in this microarray. Both TEM4-18 and TEM2-5 were then compared to PC-3 cells for changes in gene expression.