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dbSUPER specifications


Unique identifier OMICS_07448
Name dbSUPER
Restrictions to use Academic or non-commercial use
Database management system MySQL
Community driven No
Data access File download, Browse
User data submission Allowed
Content license CC Attribution
Maintained Yes


  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus



  • person_outline khana10
  • person_outline Xuegong Zhang

Publication for dbSUPER

dbSUPER citations


BACH2 immunodeficiency illustrates an association between super enhancers and haploinsufficiency

Nat Immunol
PMCID: 5593426
PMID: 28530713
DOI: 10.1038/ni.3753

[…] 3.1/functional_gene_constraint/fordist_cleaned_exac_r03_march16_z_pli_rec_null_data.txt; accessed 2016 Aug 18). We obtained super-enhancers calls (n=65,950 super-enhancers from 99 tissues/cells) from dbSuper (http://bioinfo.au.tsinghua.edu.cn/dbsuper/data/bed/hg19/all_hg19_bed.bed; accessed 2016 Aug 17). These super-enhancers were ranked according to signal intensity within each cell/tissue. We as […]


Constructing 3D interaction maps from 1D epigenomes

Nat Commun
PMCID: 4792925
PMID: 26960733
DOI: 10.1038/ncomms10812

[…] ed the binding peaks with each hotspot and non-hotspot and used hypergenomic test to compute the P value.For super enhancer data, we downloaded super enhancers in 96 human cell types/tissues from the dbSUPER website (http://bioinfo.au.tsinghua.edu.cn/dbsuper/index.php). These super enhancers were overlapped onto hotspots and non-hotspots, and the number of cell types with overlapping super enhance […]


Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex associated protein kinases

PMCID: 5224920
PMID: 27935476
DOI: 10.7554/eLife.20722.047
call_split See protocol

[…] factor regulation using the Metacore software (Thomson Reuters, New York City, New York, USA, RRID:SCR_008125). Lists of super-enhancer-associated genes were derived from published ChIP-seq datasets (dbSUPER; http://bioinfo.au.tsinghua.edu.cn/dbsuper/ and ). GSEA was performed on the super-enhancer gene lists and also genesets from MSigDB (www.broadinstitute.org/msigdb). The links for the signatur […]


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dbSUPER institution(s)
MOE Key Laboratory of Bioinformatics, Bioinformatics Division and Center for Synthetic and Systems Biology, TNLIST/Department of Automation, Tsinghua University, Beijing, China; School of Life Sciences, Tsinghua University, Beijing, China
dbSUPER funding source(s)
Supported by National Basic Research Program of China [2012CB316504]; Hi-tech Research and Development Program of China [2012AA020401]; NSFC [91010016].

dbSUPER review

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A comprehensive and interactive database of super-enhancers.