Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 12
Release date: May 12 2016
Last update date: Jan 12 2017
Access: Public
Diseases: Exanthema Subitum
Chemicals: Oxygen
Dataset link Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

Experimental Protocol


Gene expression in BMDMs obtained from wild-type and Keap1-CKO mice. In Keap1-CKO (Keap1 flox/flox::LysM-Cre) BMDMs, Nrf2 transcription factor is activated due to Keap1-deficiency. BMDMs were obtained by a culture of bone marrow cells in the presence of M-CSF for7 days. M1-activated BMDMs were obtained by stimulation with LPS and IFNg for 6 hours, while M2-activated BMDMs were obtained by a stimulation with IL-4 for 6 hours. Two independent BMDM cultures were performed, and each experiment contains samples obtained from one wild-type and one Keap1-CKO mice, respectively.

Repositories


GEO

GSE71263

ArrayExpress

E-GEOD-71263

BioProject

PRJNA290721

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