Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 24
Release date: Aug 15 2007
Last update date: Mar 17 2012
Access: Public
Diseases: Malaria
Dataset link Anopheles gambiae immune responses to human and rodent Plasmodium parasite species

Experimental Protocol


By comparing gene expression patterns between carcassess or guts of mosquitoes that fed on a P. falciparum or P. berghei wt and mosquitoes that fed on invasion incapable strains we gain information on the A. gambiae transcriptional responses to the invading ookinete at 24 hours after feeding. By comparing gene expression patterns between carcassess or guts of mosquitoes that fed on a P. falciparum ookinete invasion incapable strain and mosquitoes that fed on non-infected blood we gain information on the A. gambiae transcriptional responses to malaria infected blood in absence of ookinete invasion at 24 hours after feeding. By comparing gene expression patterns between mosquitoes at 4 hours after being injected with either E. coli or S. aureus and mosquitoes injected with sterile PBS we gain information on the mosquito's transcriptional response to these bacterial challenges.

Repositories


GEO

GSE8789

ArrayExpress

E-GEOD-8789

BioProject

PRJNA102089

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Contact


George Dimopoulos

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