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DDDPlus specifications


Unique identifier OMICS_16040
Name DDDPlus
Software type Package/Module
Interface Graphical user interface
Restrictions to use License purchase required
Input data The limited physicochemical and manufacturing data, the dissolution method
Operating system Unix/Linux
Computer skills Medium
Stability Stable
Maintained Yes


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DDDPlus citation


Justification of disintegration testing beyond current FDA criteria using in vitro and in silico models

Drug Des Devel Ther
PMCID: 5395276
PMID: 28442890
DOI: 10.2147/DDDT.S131213

[…] apparatus ii at various paddle speeds was performed for immediate and extended release formulations of metronidazole. dissolution profile fitting via ddsolver and dissolution profile predictions via dddplus™ were performed. the results showed that fickian diffusion and drug particle properties (dpp) were responsible for the dissolution of the ir tablets, and that formulation factors (eg, coning) […]

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DDDPlus institution(s)
Simulations Plus, Inc., Lancaster, CA, USA

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