Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 54
Release date: Nov 1 2015
Last update date: Feb 1 2016
Access: Public
Diseases: Neuroblastoma
Chemicals: Calcium
Dataset link Extreme sensitivity of gene expression in human neurocytes SH-SY5Y to ultra-low doses of a medicinal plant with anxiolytic-like properties

Experimental Protocol


A 54 array study that includes both SHSY5Y and IMR32 human neuroblastoma cells samples to investigate the expression changes that result in the treatment with increasing dilutions of Gelsemium sempervirens plant ethanolic extract compared to controls. Each experiment with SHSY5Y cells contained 12 samples. The neurocyte cultures were treated for 24h with 6 dilutions of the Gelsemium sempervirens extract, namely 2c, 3c, 4c, 5c, 9c, 30c (c means centesimal dilution following homeopathic Pharmacopoeia) and the corresponding 6 dilutions of the vehicle solution (controls). Four biological replicates of the experiment were analyzed. IMR32 cells were exposed to Gelsemium 2c dilution and the corresponding control in triplicate experiments.

Repositories


GEO

GSE42236

ArrayExpress

E-GEOD-42236

BioProject

PRJNA179380

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Contact


Alberto Ferrarini

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